Plasma MS300

Method Overview

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is the premier analytical technique for ultra-trace elemental and isotopic analysis. It combines the high-temperature ionization efficiency of an argon plasma with the sensitivity and selectivity of a mass spectrometer, enabling the detection and quantification of elements from lithium to uranium at parts-per-trillion (ppt) levels.

ICP-MS is indispensable for applications demanding the highest sensitivity and accuracy, including environmental monitoring, food and pharmaceutical safety, geochemical exploration, materials purity verification, and clinical research.

Plasma MS300 ICP-MS

The Plasma MS300 is a high-performance, next-generation ICP-MS system designed to deliver exceptional sensitivity, stability, and robustness for the most demanding analytical challenges. Engineered for full compliance with international regulatory standards, it provides reliable quantitative and isotopic analysis across a vast range of sample matrices—from ultrapure waters and semiconductors to complex environmental, geological, and biological materials.

Key Features & Technological Advantages

1. Superior Ion Source & Plasma Interface:

  • Compact Semiconductor RF Generator: Operates at ~27 MHz with automatic plasma matching, ensuring long-term stability and optimal performance with various sample matrices (acids, organics).

  • High-Sensitivity Interface: Features large-diameter sampler and skimmer cones (Ni or optional Pt) for maximum ion transmission and reduced maintenance frequency.

  • Low Oxide & Doubly Charged Ion Levels: Achieves CeO⁺/Ce⁺ < 2.5% and Ba⁺⁺/Ba⁺ < 4% even with a non-cooled spray chamber, minimizing spectral interferences.

2. Advanced Collision/Reaction Cell (CRC):

  • Hexapole Cell with KED Mode: Effectively removes polyatomic interferences (e.g., ⁴⁰Ar¹⁶O⁺ on ⁵⁶Fe⁺) using kinetic energy discrimination with He or H₂ gas.

  • Reaction Mode (with H₂): Eliminates specific interferences through chemical reactions (e.g., removing Ar₂⁺ to prevent overlap on Se isotopes).

3. High-Mass-Resolution Quadrupole & Detection System:

  • Fast-Scanning Quadrupole: Patented DDS (Direct Digital Synthesis) technology provides exceptional mass stability and instant switching across the mass range.

  • Mass Range: 2 – 260 amu.

  • Mass Resolution: Adjustable from 0.3 to 1.0 amu (standard operating resolution: 0.7 – 0.8 amu).

  • Dual-Mode Detector: A segmented dynode electron multiplier operates simultaneously in pulse-counting and analog modes, delivering a linear dynamic range of over 10¹⁰.

4. Efficient Vacuum System:

  • Three-zone pumping with two turbo molecular pumps and a robust backing pump.

  • Achieves operational vacuum in 5-10 minutes.

  • Equipped with protective sensors and controllers.

5. Flexible Sample Introduction System:

  • Standard system includes a peristaltic pump, glass nebulizer, and spray chamber.

  • Options for high-salt, quartz, or PFA systems for specific applications (geo/environmental, high-purity analysis).

  • Compatible with autosamplers (2 or 4 racks) and hyphenated techniques (LC-ICP-MS, GC-ICP-MS, Laser Ablation).

6. Comprehensive, User-Friendly Software:

  • Supports quantitative analysis (with calibration standards or standard addition), semi-quantitative analysis, and isotopic ratio determination.

  • Features automated QA/QC functions, interference corrections (isobaric, polyatomic, doubly charged), and internal standardization.

  • Intuitive method setup, data processing, and reporting.

Applications & Compliance

The PlasmaMS 300 is designed for universal elemental analysis with full methodological support:

  • Water Analysis: Drinking, surface, ground, and wastewater.

  • Food & Pharmaceutical Safety: Elemental profiling in foodstuffs, supplements, and pharmaceuticals.

  • Geology & Soil Science: Rock, mineral, soil analysis; isotopic dating.

  • Metals & Alloys: Composition and trace impurity analysis.

  • High-Purity Materials: Analysis of semiconductors, ultra-pure chemicals, and advanced materials.

  • Petrochemicals: Trace metals in fuels, oils, and lubricants 

  • Environmental Monitoring: Air, dust, and biological samples.

Why Choose the Plasma MS300?

  • Unmatched Sensitivity: Delivers the best-in-class detection limits for ultratrace analysis.

  • Robustness & Reliability: Engineered for high matrix tolerance and minimal downtime with easy-maintenance design.

  • Operational Flexibility: Ready for routine high-throughput analysis and advanced research applications, including hyphenation.

  • Expert Support & Configuration: Our specialists provide tailored instrument configuration, method development, and ongoing technical support.

The Plasma MS300 represents the pinnacle of ICP-MS technology, offering laboratories a definitive tool for achieving the highest levels of analytical accuracy, productivity, and compliance in elemental analysis

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